It can increase some of the side effects of metoclopramide. Metoclopramide here may suppress, or Metocontin suppress, the signs of TD, use that masking the underlying disease process. Metoclopramide inhibits the central and peripheral effects of apomorphine, induces release of prolactin and causes a transient increase in circulating aldosterone levels, which may be associated with transient fluid retention. Subsequent studies showed relief of pain with the use of metoclopramide alone.
Possible side effects of Metocontin include:
Metocontin is used to treat diseases such as: Gastroparesis, GERD, Lactation Augmentation, Migraine, Nausea/Vomiting, Nausea/Vomiting, Chemotherapy Induced, Nausea/Vomiting, Postoperative, Radiographic Exam, Small Intestine Intubation.
After 4 days, the dosage may be increased to 348 mg, taken once daily in the morning. CNS depressant effect may occur when it is combined with other CNS depressants including anxiolytics, sedatives, and hypnotics, such as ramelteon.